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Wiley InterScience | ||||||||||
  Headache: The Journal of Head and Face PainVolume 20 Issue 4, Pages 204 - 207 Published Online: 22 Jun 2005 © 2010 American Headache Society Published on behalf of the American Headache Society
Abstract | Full Text: PDF (Size: 32K) | Related Articles | Citation Tracking  Comparative Trial of Tenormin (Atenolol) and Inderal (Propranolol) in Migraine Copyright © 1980 American Headache Society (formerly the American Association for the Study of Headache) ABSTRACTSYNOPSIS Atenolol, 50 mg, b.i.d., and propranolol, 80 mg b.i.d., were given to 28 patients with a presumed diagnosis of migraine, in a placebo-controlled double-blind cross-over study, where each period lasted 6 weeks. In the total material, atenolol was significantly better than placebo in reducing attacks, whereas propranolol showed no definite such effect. In seven patients, the number of headache days was remarkably high (average: 22 headache days in 42 days), which may indicate that they have been inappropriately included in the material or have recorded interparoxysmal headache in addition to attacks. If these patients are excluded, the attack-reducing effects of both propranolol and atenolol are significant and of equal magnitude. Accepted for Publication: January 5, 1980. | 
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