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Wiley InterScience | |||||||||
  British Journal of DermatologyVolume 100 Issue 2, Pages 207 - 212 Published Online: 29 Jul 2006 Journal compilation © 2010 British Association of Dermatologists An Official Journal of the British Association of Dermatologists
Abstract | References | Full Text: PDF (Size: 1984K) | Related Articles | Citation Tracking  Hereditary angio-oedema: treatment with danazol REPORT OF A CASE Copyright 1979 British Association of Dermatologists ABSTRACT
An 8-year-old boy with hereditary angio-oedema was treated with danazol under close endocrinological supervision. The boy's C1 esterase inhibitor (Clinh) and C4 levels increased rapidly to near normal values under a daily doses of 400 mg and were maintained at about 50% of the normal by maintenance doses of 200 mg danazol every other day. Throughout the entire treatment period (11 months) the boy has been maintained free from attacks of angio-oedema. No hormonal imbalance was detected in the follow-up period. Our results indicate that danazol should be suitable for the treatment of HAE not only in adults but also in prepubescent children. Accepted for publication 19 June 1978 | 
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