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Wiley InterScience | |||||||||
  British Journal of DermatologyVolume 100 Issue 6, Pages 687 - 692 Published Online: 29 Jul 2006 Journal compilation © 2010 British Association of Dermatologists An Official Journal of the British Association of Dermatologists
Abstract | References | Full Text: PDF (Size: 1970K) | Related Articles | Citation Tracking  The effect of topically applied progesterone on sebum excretion rate Copyright 1979 British Association of Dermatologists ABSTRACT
There is evidence that anti-androgens may help in the treatment of acne vulgaris. We therefore performed a double-blind trial to assess the effect of topically applied progesterone on sebum excretion rate. Thirty-eight patients took part in the trial which was for 3 months. The preparation had no etfect in males. However, a signiticant reduction in sebum excretion rate was found in females, the etfect being maximal at the end of the second month. There was a significant loss of effect at the end of the third month and this was not related to deterioration of the progesterone preparation. Accepted for publication 29 October 1978 | 
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