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Wiley InterScience | |||||||||||||||||||
  Journal of Child Psychology and PsychiatryVolume 16 Issue 4, Pages 289 - 299 Published Online: 7 Dec 2006 Journal Compilation © 2010 ACAMH Published on behalf of the Association for Child and Adolescent Mental Health
Abstract | References | Full Text: PDF (Size: 718K) | Related Articles | Citation Tracking  IMIPRAMINE IN ENURESIS—PSYCHOLOGICAL AND PHYSIOLOGICAL EFFECTS Copyright 1975 Association for Child Psychology and Psychiatry KEYWORDS imipramine • enuresis • effects ABSTRACTImipramine was given in a single nocturnal dose of 50 mg to 24 mostly psychiatrically normal, enuretic boys for three weeks in a double-blind, placebo-controlled, crossover trial to determine what effects the drug was having on systems other than the urinary tract. Behavioural changes, mostly of a positive kind, slight weight loss, tachycardia, raised diastolic blood pressure and cognitivie changes occurred, suggesting that the effect of the drug in children is analogous to that of the stimulants, at least over a three week period. This would also suggest that the effect of anti-depressants in normal subjects is no different from that in depressed patients, though the findings of this study require replication. Accepted manuscript received 20 October 1974 | 
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 | 50th Anniversary Special Issue |
 | The Journal of Child Psychology and Psychiatry |
