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Wiley InterScience

British Journal of Dermatology

British Journal of Dermatology

Volume 89 Issue 5, Pages 487 - 490

Published Online: 29 Jul 2006

Journal compilation © 2010 British Association of Dermatologists



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Reduction of sebum excretion in man by the antiandrogen, cyproterone acetate
J.L. BURTON* 1 , URSULA LASCHET SAM SHUSTER 1
  1 Wellcome Laboratories for Research into Skin Disease, University Department of Dermatology, Newcastle-upon-Tyne   Pfälzische Nervenklinik, Psychendokrinologische Abteilung, 6749 Landeck/Pfalz, Germany
 

*Department of dermatology, Royal Infirmary, Bristol.

Copyright 1973 British Association of Dermatologists

ABSTRACT

AbstractREFERENCES

The effect of systemic cyproterone acetate on sebaceous activity was studied in twenty male patients being tested for sexual offences. In every patient the sebum excretion rate (SER) was below the mean SER of untreated normal male subjects of the same age, and the mean SER for the treated male patients was significantly lower than in a control group of normal females. The degree of reduction in SER produced by cyproterone acetate confirms that androgen is a major sebotrophic factor in the human male.


Accepted for publication 7 March 1973

DIGITAL OBJECT IDENTIFIER (DOI)
10.1111/j.1365-2133.1973.tb03009.x About DOI

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