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Wiley InterScience | ||||
![]() British Journal of DermatologyVolume 89 Issue 5, Pages 487 - 490 Published Online: 29 Jul 2006 Journal compilation © 2010 British Association of Dermatologists An Official Journal of the British Association of Dermatologists
Abstract | References | Full Text: PDF (Size: 203K) | Related Articles | Citation Tracking Reduction of sebum excretion in man by the antiandrogen, cyproterone acetate Copyright 1973 British Association of Dermatologists ABSTRACT
The effect of systemic cyproterone acetate on sebaceous activity was studied in twenty male patients being tested for sexual offences. In every patient the sebum excretion rate (SER) was below the mean SER of untreated normal male subjects of the same age, and the mean SER for the treated male patients was significantly lower than in a control group of normal females. The degree of reduction in SER produced by cyproterone acetate confirms that androgen is a major sebotrophic factor in the human male. Accepted for publication 7 March 1973 |