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Wiley InterScience | ||||||||||
  BJOG: An International Journal of Obstetrics & GynaecologyVolume 80 Issue 4, Pages 349 - 352 Published Online: 23 Aug 2005 Journal compilation © 2010 RCOG Published on behalf of the Royal College of Obstetricians and Gynaecologists
Abstract | References | Full Text: PDF (Size: 285K) | Related Articles | Citation Tracking  BLOOD LEVELS OF D1AZEPAM IN INFANTS OF TWO MOTHERS GIVEN LARGE DOSES OF DIAZEPAM DURING LABOUR *Bristol Royal Hospital for Sick Children, St. Michael's Hill, Bristol, BS2 8BJ.
Copyright RCOG 1973 BJOG: an International Journal of Obstetrics and Gynaecology ABSTRACT
Two babies are described whose mothers were given large doses of diazepam during labour. One mother had eclampsia, and the other had severe pre-eclampsia. Both babies were severely asphyxiated at birth, and one showed depressed respirations and reflexes for four days. The blood levels of diazepam in both babies rose for 40 hours after birth and then fell suddenly but remained detectable until the seventh day of life. The metabolism of the drug in the perinatal period is discussed. | 
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