Low-dose acyclovir for HSV-2 meningitis in a child

doi:10.1111/j.1651-2227.2004.tb02728.x

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Wiley InterScience

Acta Pædiatrica

Volume 93 Issue 8, Pages 1123 - 1124

Published Online: 2 Jan 2007

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Low-dose acyclovir for HSV-2 meningitis in a child

SA Kohlhoff ¹ , TA Marciano ¹ SA Rawstron ¹

¹ Department of Pediatrics, State University of New York Downstate Medical Center, Brooklyn, New York, USA

Correspondence to Stephan Kohlhoff, Department of Pediatric Infectious Diseases, SUNY Downstate Medical Center, 450 Clarkson Ave, Box 49 Brooklyn NY 11217, USA (Tel. +1 718 270 2996, fax. +1 718 270 3210, e-mail. stephan.kohlhoff@downstate.edu)

KEYWORDS

Low-dose acyclovir • HSV-2 meningitis • child

ABSTRACT

A 7-y-old girl with genital herpes following sexual abuse presented with dysuria, fever and meningeal signs. Acyclovir (15 mg/kg/d for 10 d) was administered for severe genitourinary symptoms. The CSF culture was positive for HSV type 2.

Conclusion: Complete resolution of all symptoms demonstrates that, as in adults, HSV-2 meningitis does not require high-dose or prolonged acyclovir therapy.

Received Dec. 30, 2003; accepted Feb. 13, 2004

DIGITAL OBJECT IDENTIFIER (DOI)

10.1111/j.1651-2227.2004.tb02728.x About DOI