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Treatment of External Genital Warts
Alex Ferenczy, MD
  Department of Pathology, The Sir Mortimer B. Davies Jewish General Hospital, and
McGill University, Montreal, Quebec, Canada
Correspondence to Reprint requests to: Alex Ferenczy, MD, Department of Pathology, The Sir Mortimer B. Davies Jewish General Hospital, Montreal, Quebec, Canada.

This article was presented as a paper at the 10th World Congress of Cervical Pathology and Colposcopy, November 7–11, 1999, Buenos Aires, Argentina.

Copyright 2000 ASCCP
KEYWORDS
external genital warts • human papillomavirus • imiquimod • recurrence • treatment

ABSTRACT

Abstract: To date the most widely used therapies for the treatment of external genital warts (EGWs) have been ablative techniques, some of which have serious side effects and result in high recurrence. This is frustrating for both patients and physicians. More recently, patient-applied therapies have become available, which offer several advantages over provider-administered therapies, and are generally preferred by the patients. The newest of these is imiquimod 5% cream. Its mode of action, stimulating the immune system to deal with the human papillomavirus (HPV), provides an effective treatment. Results obtained in clinical trials with imiquimod are described here, in the context of a recommended treatment protocol for EGWs. In addition, the potential for imiquimod to treat other HPV lesions is discussed.


DIGITAL OBJECT IDENTIFIER (DOI)
10.1046/j.1526-0976.2000.43003.x About DOI

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