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Wiley InterScience

International Journal of Dermatology

International Journal of Dermatology

Volume 38 Issue 12, Pages 928 - 930

Published Online: 25 Dec 2001

Journal compilation © 2010 International Society of Dermatology



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CLINICAL TRIAL
Improvement in androgenetic alopecia in 53–76-year-old men using oral finasteride
Sarah Brenner MD and Hagit Matz MD,
  Department of Dermatology, Tel Aviv Sourasky Medical Center and Sackler Faculty of Medicine, . Tel Aviv University, Tel Aviv,. Israel
Correspondence
Sarah Brenner, md
Department of Dermatology
Tel Aviv Sourasky Medical Center
6 Weizman Street
Tel Aviv 64239
Israel
Copyright 1999 Blackwell Science Ltd

ABSTRACT

Twenty-eight men with AGA, aged 53–76 years (mean, 65 years), were selected to participate in this trial from a double blind, placebo controlled, multicenter study of subjects with moderate symptoms of BPH. Patients received either finasteride 5 mg or placebo daily for 24 months. Hair counts were performed at entry to the study and at 6, 12, 18, and 24 months. Hair counts were made directly on the scalp in a circular target area 1 in in diameter, located in the center of a template. The template was applied in such a way that its counting window fell on the most balding scalp area, which remained the same for each patient. 11At each hair counting session, patients were asked about side-effects and questioned about their sex life. Time trend and differences between groups were examined using a one-way (treatment) MANOVA with repeated measures (baseline, 6, 12, 18, and 24 months). Additional two-tailed t-tests were performed to compare the two groups at each point of time. P <  0.05 was considered to be significant.


DIGITAL OBJECT IDENTIFIER (DOI)
10.1046/j.1365-4362.1999.00804.x About DOI

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