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Wiley InterScience

Australian Veterinary Journal

Australian Veterinary Journal

Volume 78 Issue 5, Pages 320 - 325

Published Online: 10 Mar 2008

Journal compilation © 2010 Australian Veterinary Association



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Disseminated Mycobacterium avium infection in a dog with chronic diarrhoea
B HORN a , D FORSHAW b , D COUSINS c PJ IRWIN a
  a School of Veterinary Clinical Science, Division of Veterinary and Biomedical Sciences, Murdoch University, South St, Murdoch, Western Australia 6150   b Animal Health Laboratories, Agriculture Western Australia, 444 Albany Hwy, Albany, Western Australia 6330   c Animal Health Laboratories, Agriculture Western Australia, Baron-Hay Court, South Perth, Western Australia 6151
Copyright 2000 The Journal of the Australian Veterinary Association
KEYWORDS
Diarrhoea • acid-fast bacilli • Mycobacterium avium • mycobacteriosis • disseminated • dog

ABSTRACT

A 3-year-old Maltese-cross dog presented with a 4-month history of chronic diarrhoea and inappetence. Poorly regenerative anaemia, leukocytosis and hypoproteinaemia were evident on several occasions. Biopsies of stomach, duodenum and colon revealed marked infiltration of mucosae by macrophages containing many acid-fast bacilli. Similar organisms were numerous in a faecal smear. Melaena, haematochezia and severe abdominal pain developed and were unresponsive to therapy. Following euthanasia and necropsy, histiocytic cells containing acid-fast bacilli were found throughout the gastrointestinal tract, mesenteric and peripheral lymph nodes, spleen, liver, kidney and lungs. The organism was identified as Mycobacterium avium by bacterial culture and polymerase chain reaction testing.


Accepted for publication 28 October 1999

DIGITAL OBJECT IDENTIFIER (DOI)
10.1111/j.1751-0813.2000.tb11781.x About DOI

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