|
If you are seeing this message, you may be experiencing temporary network problems. Please wait a few minutes and refresh the page. If the problem persists, you may wish to report it to your local Network Manager.
It is also possible that your web browser is not configured or not able to display style sheets. In this case, although the visual presentation will be degraded, the site should continue to be functional. We recommend using the latest version of Microsoft or Mozilla web browser to help minimise these problems.
Wiley InterScience | ||
  Cellular MicrobiologyVolume 4 Issue 4, Pages 201 - 211 Published Online: 22 Nov 2002 © 2010 Blackwell Publishing Ltd
Abstract | References | Full Text: HTML, PDF (Size: 890K) | Related Articles | Citation Tracking 
Yersinia effectors target mammalian signalling pathways Copyright Blackwell Science Ltd ABSTRACTAnimals have an immune system to fight off challenges from both viruses and bacteria. The first line of defence is innate immunity, which is composed of cells that engulf pathogens as well as cells that release potent signalling molecules to activate an inflammatory response and the adaptive immune system. Pathogenic bacteria have evolved a set of weapons, or effectors, to ensure survival in the host. Yersinia spp. use a type III secretion system to translocate these effector proteins, called Yops, into the host. This report outlines how Yops thwart the signalling machinery of the host immune system.
|
