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Wiley InterScience | ||||||||
  American Journal of TransplantationVolume 1 Issue 1, Pages 93 - 95 Published Online: 17 Sep 2008 © 2010 American Society of Transplantation and the American Society of Transplant Surgeons
Abstract | References | Full Text: HTML, PDF (Size: 52K) | Related Articles | Citation Tracking  Fatal Disseminated Aspergillosis following Sequential Heart and Stem Cell Transplantation for Systemic Amyloidosis Copyright Munksgaard International Publishers Ltd, 2001 KEYWORDS Amyloidosis • aspergillosis • heart transplant • stem cell transplant ABSTRACTInfectious complications are a major cause of morbidity and mortality in transplant recipients. We describe a case of fatal disseminated aspergillosis immediately following autologous peripheral stem cell reconstitution in a patient who had undergone orthotopic heart transplantation for systemic amyloidosis. The case described suggests that the infectious risks in patients undergoing these sequential procedures may be distinct from those occurring in patients undergoing either procedure independently. Potential prophylactic and therapeutic interventions are discussed. Since this experimental and evolving approach for the management of systemic amyloidosis is potentially applicable to a limited number of patients, multicenter collaboration may be needed to further define the infectious risks in this unique subset of transplant recipients. Received 18 October 2000, revised and accepted for publication 20 December 2000 | 
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