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Wiley InterScience | |||||||||||||||||||
  Acta Psychiatrica ScandinavicaVolume 86 Issue S369, Pages 51 - 58 Published Online: 23 Aug 2007 © 2010 John Wiley & Sons A/S
Abstract | References | Full Text: PDF (Size: 713K) | Related Articles | Citation Tracking  Controlled trials of Antabuse in alcoholism: the importance of supervision and adequate dosage Copyright 1992 Blackwell Publishing Ltd KEYWORDS Antabuse • disulfiram • effectiveness • supervision • compliance ABSTRACTMethods of using Antabuse have changed since its introduction over 40 years ago. Several randomised controlled trials have shown that Antabuse can make a statistically and clinically significant contribution to treatment outcome in alcoholism but only if its administration is carefully supervised. The recent literature is reviewed. Adequate dosage is important and the recommended maximum in some countries is often insufficient. Both prescribes and supervisors of Antabuse need to be aware of the ways in which some patients try to evade medication. | 
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 | Personality and Mental Health |
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