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Predictors of transfusion for spinal surgery in Maryland, 1997 to 2000
Sean M. Berenholtz , Peter J. Pronovost , Daniel Mullany , Elizabeth Garrett , Paul M. Ness , Todd Dorman , and Michael J. Klag
  From the Departments of Anesthesiology/Critical Care Medicine, Medicine, Surgery, Oncology, Pathology, and Health Policy and Management, The Johns Hopkins University Schools of Medicine and Hygiene and Public Health, Baltimore, Maryland.
Correspondence to Address reprint requests to: Sean Berenholtz, MD, The Johns Hopkins Hospital, Department of Anesthesiology, 600 North Wolfe Street, Halsted 842, Baltimore, MD 21287-5842; e-mail: sberenho@jhmi.edu.

ABBREVIATIONS: HSCRC = Health Services Cost Review Commission; ICD-9-CM = International Classification of Diseases, 9th revision, clinical modification.

Supported in part by a grant from the Eugene and Mary B. Meyer Center for Advanced Transfusion Practices and Blood Research at Johns Hopkins University and by a Clinician Scientist Award from The Johns Hopkins University.

Copyright 2002 American Association of Blood Banks

ABSTRACT

BACKGROUND: The purpose of this study was to identify preoperative patient, hospital, and surgeon characteristics associated with transfusion for spinal surgery.

STUDY DESIGN AND METHODS: Discharge data were obtained from 39 Maryland hospitals for adult patients (n = 3988) who had a primary procedure code for spinal surgery between July 1997 through June 2000, and with these codes, surgeons and hospitals were characterized by annual patient volume. Outcome variables included any allogeneic transfusion, any transfusion, RBCs, autologous blood, FFP, or platelet transfusion. Logistic regression was used for univariate and multivariate analyses.

RESULTS: Characteristics independently associated with an increased risk of receiving any allogeneic transfusion (n = 786) included age >54 (OR, 1.6; 95% CI, 1.3-2.1), age >66 (OR, 2.7; 95% CI, 2.0-3.5), female sex (OR, 1.6; 95% CI, 1.2-2.0), diabetes with chronic complications (OR, 2.5; 95% CI, 1.3-4.9), and metastatic tumor (OR, 4.9; 95% CI, 2.3-10.5), emergency room admission (OR, 2.3; 95% CI, 1.4-3.8), and greater hospital volume (OR, 4.0; 95% CI, 1.8-8.6). Characteristics independently associated with increased autologous transfusions (n = 574) included white race (OR, 1.7; 95% CI, 1.2-2.4), female sex (OR, 1.4; 95% CI, 1.1-1.8), and greater surgeon volume (OR, 3.5; 95% CI, 1.4-9.1).

DISCUSSION: This information can be used to provide informed risk-benefit discussions with patients regarding the risk for blood transfusion as well as to target high-risk patients and institutions for interventions to reduce the risk of exposure to blood components.


Received for publication July 12, 2001; revision received September 10, 2001, and accepted September 28, 2001.

DIGITAL OBJECT IDENTIFIER (DOI)
10.1046/j.1537-2995.2002.00034.x About DOI

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