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Wiley InterScience

JOURNALS

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Early View

(Articles online in advance of print)

Cell Culture and Tissue Engineering

The roles of apoptotic pathways in the low recovery rate after cryopreservation of dissociated human embryonic stem cells (p NA)
Xia Xu, Sally Cowley, Christopher J. Flaim, William James, Leonard Seymour, Zhanfeng Cui
Published Online: Jan 13 2010 2:13PM
DOI: 10.1002/btpr.368

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Applied Cellular Physiology and Metabolic Engineering

Optimization of the expression of recombinant human activin A in the yeast Pichia pastoris (p NA)
Dale Fredericks, Robert Clay, Tracy Warner, Anne O'Connor, David M. de Kretser, Milton T. W. Hearn
Published Online: Jan 13 2010 1:31PM
DOI: 10.1002/btpr.304

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Process Sensing and Control

Alcohol biosensing by polyamidoamine (PAMAM)/cysteamine/alcohol oxidase-modified gold electrode (p NA)
Mehriban Akin, Merve Yuksel, Caner Geyik, Dilek Odaci, Arne Bluma, Tim Höpfner, Sascha Beutel, Thomas Scheper, Suna Timur
Published Online: Jan 13 2010 11:01AM
DOI: 10.1002/btpr.372

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Development and optimization of a process for automated recovery of single cells identified by microengraving (p NA)
Jae Hyeok Choi, Adebola O. Ogunniyi, Mindy Du, Minna Du, Marcel Kretschmann, Jens Eberhardt, J. Christopher Love
Published Online: Jan 8 2010 11:03AM
DOI: 10.1002/btpr.374

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Bioseparations and Downstream Processing

A novel Method for the selective recovery and purification of gamma-polyglutamic acid from Bacillus licheniformis fermentation broth (p NA)
Bhavik Manocha, Argyrios Margaritis
Published Online: Jan 8 2010 11:03AM
DOI: 10.1002/btpr.370

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Review Articles: Applied Cellular Physiology and Metabolic Engineering

Modeling with a view to target identification in metabolic engineering: A critical evaluation of the available tools (p NA)
Jo Maertens, Peter A. Vanrolleghem
Published Online: Jan 5 2010 10:58AM
DOI: 10.1002/btpr.349

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Cell Culture and Tissue Engineering

Perfusion seeding of channeled elastomeric scaffolds with myocytes and endothelial cells for cardiac tissue engineering (p NA)
Robert Maidhof, Anna Marsano, Eun Jung Lee, Gordana Vunjak-Novakovic
Published Online: Jan 5 2010 10:58AM
DOI: 10.1002/btpr.337

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Review Article: Cell Culture and Tissue Engineering

Technological progresses in monoclonal antibody production systems (p NA)
Maria Elisa Rodrigues, Ana Rita Costa, Mariana Henriques, Joana Azeredo, Rosário Oliveira
Published Online: Dec 30 2009 11:07AM
DOI: 10.1002/btpr.348

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Bioseparations and Downstream Processing

Impact of freezing on pH of buffered solutions and consequences for monoclonal antibody aggregation (p NA)
Parag Kolhe, Elizabeth Amend, Satish K. Singh
Published Online: Dec 28 2009 3:58PM
DOI: 10.1002/btpr.377

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Process Sensing and Control

Product and contaminant measurement in bioprocess development by SELDI-MS (p NA)
Alex Berrill, Sa V. Ho, Daniel G. Bracewell
Published Online: Dec 28 2009 3:42PM
DOI: 10.1002/btpr.376

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Cell Culture and Tissue Engineering

A cell leakproof PLGA-collagen hybrid scaffold for cartilage tissue engineering (p NA)
Naoki Kawazoe, Chieko Inoue, Tetsuya Tateishi, Guoping Chen
Published Online: Dec 28 2009 3:42PM
DOI: 10.1002/btpr.375

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Bioseparations and Downstream Processing

Disaggregation of high-molecular weight species during downstream processing to recover functional monomer (p NA)
Xuankuo Xu, David M. Didio, Kirk J. Leister, Sanchayita Ghose
Published Online: Dec 28 2009 3:31PM
DOI: 10.1002/btpr.373

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Biocatalysts and Bioreactor Design

Microwave-based alkali pretreatment of switchgrass and coastal bermudagrass for bioethanol production (p NA)
Deepak R. Keshwani, Jay J. Cheng
Published Online: Dec 28 2009 3:31PM
DOI: 10.1002/btpr.371

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Effect of disaccharides on the stabilization of bovine trypsin against detergent and autolysis (p NA)
Shivcharan Prasad, Ipsita Roy
Published Online: Dec 28 2009 2:46PM
DOI: 10.1002/btpr.367

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Process Sensing and Control

Using the rate of respiration to monitor events in the infection of Escherichia coli cultures by bacteriophage T4 (p NA)
Dominic Sauvageau, Béatrice Allain, David G. Cooper
Published Online: Dec 28 2009 2:46PM
DOI: 10.1002/btpr.365

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Tag SNP selection using particle swarm optimization (p NA)
Li-Yeh Chuang, Cheng-San Yang, Chang-Hsuan Ho, Cheng-Hong Yang
Published Online: Dec 28 2009 2:11PM
DOI: 10.1002/btpr.350

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Bioseparations and Downstream Processing

Techno-economic evaluation of a two-step biological process for hydrogen production (p NA)
Mattias Ljunggren, Guido Zacchi
Published Online: Dec 28 2009 1:31PM
DOI: 10.1002/btpr.336

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Cell Culture and Tissue Engineering

A multiparallel bioreactor for the cultivation of mammalian cells in a 3D-ceramic matrix (p NA)
Rudibert King
Published Online: Dec 28 2009 12:14PM
DOI: 10.1002/btpr.335

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Process Sensing and Control

pH measurement and a rational and practical pH control strategy for high throughput cell culture system (p NA)
Haiying Zhou, Jennifer Purdie, Tongtong Wang, Anli Ouyang
Published Online: Dec 28 2009 11:51AM
DOI: 10.1002/btpr.369

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Biocatalysts and Bioreactor Design

Switchgrass leaching requirements for solid-state fermentation by Acidothermus cellulolyticus (p NA)
Jean S. VanderGheynst, Farzaneh Rezaei, Todd M. Dooley, Alison M. Berry
Published Online: Dec 28 2009 11:39AM
DOI: 10.1002/btpr.366

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Cell Culture and Tissue Engineering

Accurate control of oxygen level in cells during culture on silicone rubber membranes with application to stem cell differentiation (p NA)
Daryl E. Powers, Jeffrey R. Millman, Susan Bonner-Weir, Michael J. Rappel, Clark K. Colton
Published Online: Dec 28 2009 11:28AM
DOI: 10.1002/btpr.359

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Biocatalysts and Bioreactor Design

Functionalization of cellulose acetate fibers with engineered cutinases (p NA)
Teresa Matamá, Rita Araújo, Georg M. Gübitz, Margarida Casal, Artur Cavaco-Paulo
Published Online: Dec 15 2009 1:26PM
DOI: 10.1002/btpr.364

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Applied Cellular Physiology and Metabolic Engineering

Enantioselective oxidation of 2-hydroxy carboxylic acids by glycolate oxidase and catalase coexpressed in methylotrophic Pichia pastoris (p NA)
Shuvendu Das, James H. Glenn IV, Mani Subramanian
Published Online: Dec 15 2009 1:26PM
DOI: 10.1002/btpr.363

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Bioseparations and Downstream Processing

Application of agent-based system for bioprocess description and process improvement (p NA)
Ying Gao, Katie Kipling, Jarka Glassey, Mark Willis, Gary Montague, Yuhong Zhou, Nigel J. Titchener-Hooker
Published Online: Dec 15 2009 1:26PM
DOI: 10.1002/btpr.361

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Applied Cellular Physiology and Metabolic Engineering

Importance of NADPH supply for improved L-valine formation in Corynebacterium glutamicum (p NA)
Tobias Bartek, Bastian Blombach, Enrico Zönnchen, Pia Makus, Siegmund Lang, Bernhard J. Eikmanns, Marco Oldiges
Published Online: Dec 15 2009 11:42AM
DOI: 10.1002/btpr.345

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Cell Culture and Tissue Engineering

Feed development for fed-batch CHO production process by semisteady state analysis (p NA)
Sarwat F. Khattak, Zizhuo Xing, Brian Kenty, Inna Koyrakh, Zheng Jian Li
Published Online: Dec 11 2009 11:51AM
DOI: 10.1002/btpr.362

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Active and inactive metabolic pathways in tumor spheroids: Determination by GC-MS (p NA)
Michael G. Hunnewell, Neil S. Forbes
Published Online: Dec 11 2009 11:22AM
DOI: 10.1002/btpr.360

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Enhancement of cell recovery for dissociated human embryonic stem cells after cryopreservation (p NA)
Xia Xu, Sally Cowley, Christopher J. Flaim, William James, Lenard W. Seymour, Zhanfeng Cui
Published Online: Dec 11 2009 11:03AM
DOI: 10.1002/btpr.358

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Bioseparations and Downstream Processing

High-throughput screening techniques for rapid PEG-based precipitation of IgG4 mAb from clarified cell culture supernatant (p NA)
Carol Knevelman, Jim Davies, Lee Allen, Nigel J. Titchener-Hooker
Published Online: Dec 11 2009 10:48AM
DOI: 10.1002/btpr.357

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Cell Culture and Tissue Engineering

Maintenance of pluripotency in mouse embryonic stem cells cultivated in stirred microcarrier cultures (p NA)
Paulo A. N. Marinho, Aline M. Fernandes, Juliana C. Cruz, Stevens K. Rehen, Leda R. Castilho
Published Online: Dec 11 2009 10:48AM
DOI: 10.1002/btpr.328

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Biocatalysts and Bioreactor Design

Experimental and theoretical assessment of maximum productivities for the microalgae Chlamydomonas reinhardtii in two different geometries of photobioreactors (p NA)
Hosni Takache, Gwendoline Christophe, Jean-François Cornet, Jérémy Pruvost
Published Online: Dec 1 2009 10:51AM
DOI: 10.1002/btpr.356

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Production and characterization of poly-3-hydroxybutyrate from biodiesel-glycerol by Burkholderia cepacia ATCC 17759 (p NA)
Chengjun Zhu, Christopher T. Nomura, Joseph A. Perrotta, Arthur J. Stipanovic, James P. Nakas
Published Online: Dec 1 2009 10:25AM
DOI: 10.1002/btpr.355

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Improvement of ganoderic acid and Ganoderma polysaccharide biosynthesis by Ganoderma lucidum fermentation under the inducement of Cu2+ (p NA)
Ya-Jie Tang, Li-Wen Zhu
Published Online: Dec 1 2009 10:05AM
DOI: 10.1002/btpr.352

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Note: Applied Cellular Physiology and Metabolic Engineering

Secreted production of Renilla luciferase in Bacillus subtilis (p NA)
Chung-Jen Chiang, Po Ting Chen, Yun-Peng Chao
Published Online: Dec 1 2009 10:05AM
DOI: 10.1002/btpr.351

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Process Sensing and Control

Population estimation of human embryonic stem cell cultures (p NA)
Thomas Thurnherr, Andre Choo, Ivan Reading, Steve K. W. Oh
Published Online: Nov 25 2009 12:23PM
DOI: 10.1002/btpr.344

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Cell Culture and Tissue Engineering

Cell surface display of highly pathogenic avian influenza virus hemagglutinin on the surface of Pichia pastoris cells using alpha-agglutinin for production of oral vaccines (p NA)
Jamie L. Wasilenko, Luciana Sarmento, Stephen Spatz, Mary Pantin-Jackwood
Published Online: Nov 30 2009 8:46AM
DOI: 10.1002/btpr.343

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Biocatalysts and Bioreactor Design

Multicomponent cellulase production by Cellulomonas biazotea NCIM-2550 and its applications for cellulosic biohydrogen production (p NA)
Ganesh D. Saratale, Rijuta G. Saratale, Yung-Chung Lo, Jo-Shu Chang
Published Online: Nov 25 2009 11:51AM
DOI: 10.1002/btpr.342

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Bioseparations and Downstream Processing

Protein recovery from enzyme-assisted aqueous extraction of soybean (p NA)
Kerry A. Campbell, Charles E. Glatz
Published Online: Nov 25 2009 11:51AM
DOI: 10.1002/btpr.341

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Separation of astaxanthin from cells of Phaffia rhodozyma using colloidal gas aphrons in a flotation column (p NA)
Maria Dermiki, Anne Lise Bourquin, Paula Jauregi
Published Online: Nov 25 2009 11:35AM
DOI: 10.1002/btpr.340

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Note: Biocatalysts and Bioreactor Design

Power consumption and maximum energy dissipation in a milliliter-scale bioreactor (p NA)
Ralf Hortsch, Dirk Weuster-Botz
Published Online: Nov 25 2009 11:35AM
DOI: 10.1002/btpr.338

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Biocatalysts and Bioreactor Design

Endo- and exo-inulinases: Enzyme-substrate interaction and rational immobilization (p NA)
Alessandra Basso, Patrizia Spizzo, Valerio Ferrario, Lorena Knapic, Nina Savko, Paolo Braiuca, Cynthia Ebert, Emanuele Ricca, Vincenza Calabrò, Lucia Gardossi
Published Online: Nov 25 2009 11:35AM
DOI: 10.1002/btpr.334

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Bioseparations and Downstream Processing

Mimic of a large-scale diafiltration process by using ultra scale-down rotating disc filter (p NA)
Guijun Ma, Jean Aucamp, Spyridon Gerontas, Ranna Eardley-Patel, Alan Craig, Mike Hoare, Yuhong Zhou
Published Online: Nov 24 2009 11:54AM
DOI: 10.1002/btpr.327

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Wet-milling transgenic maize seed for fraction enrichment of recombinant subunit vaccine (p NA)
Lorena Moeller, Raye Taylor-Vokes, Steve Fox, Qinglei Gan, Lawrence Johnson, Kan Wang
Published Online: Nov 24 2009 11:39AM
DOI: 10.1002/btpr.326

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Biocatalysts and Bioreactor Design

Understanding the key factors for enzymatic conversion of pretreated lignocellulose by partial least square analysis (p NA)
Renliang Huang, Rongxin Su, Wei Qi, Zhimin He
Published Online: Nov 24 2009 11:39AM
DOI: 10.1002/btpr.324

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Cell Culture and Tissue Engineering

Regulation of XBP-1 signaling during transient and stable recombinant protein production in CHO cells (p NA)
Sebastian C. Y. Ku, Poh Choo Toh, Yih Yean Lee, Janet Chusainow, Miranda G. S. Yap, Sheng-Hao Chao
Published Online: Nov 24 2009 11:09AM
DOI: 10.1002/btpr.322

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Assessment of embryonic growth in chicken eggs by means of visible transmission spectroscopy (p NA)
Bart J. Kemps, Flip R. Bamelis, Kristof Mertens, Eddy M. Decuypere, Josse G. De Baerdemaeker, Bart De Ketelaere
Published Online: Nov 24 2009 11:09AM
DOI: 10.1002/btpr.321

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A noninvasive technique for the measurement of the energetic state of free-suspension mammalian cells (p NA)
M. Ben-Tchavtchavadze, J. Chen, Michel Perrier, Mario Jolicoeur
Published Online: Nov 24 2009 10:55AM
DOI: 10.1002/btpr.333

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Note: Cell Culture and Tissue Engineering

Development of multilayered cell-hydrogel composites using an acoustic focusing technique (p NA)
Jason P. Mazzoccoli, Donald L. Feke, Harihara Baskaran, Peter N. Pintauro
Published Online: Nov 24 2009 10:37AM
DOI: 10.1002/btpr.332

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Biocatalysts and Bioreactor Design

Stimulation of glucose oxidase with white linearly polarized light (p NA)
Anna Konieczna-Molenda, Maciej Fiedorowicz, Przemyslstrokaw J. Tomasik
Published Online: Nov 24 2009 10:37AM
DOI: 10.1002/btpr.330

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Cell Culture and Tissue Engineering

Application of near-infrared (NIR) spectroscopy for screening of raw materials used in the cell culture medium for the production of a recombinant therapeutic protein (p NA)
Alime Ozlem Kirdar, Guoxiang Chen, James Weidner, Anurag S. Rathore
Published Online: Nov 24 2009 10:37AM
DOI: 10.1002/btpr.329

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Bioseparations and Downstream Processing

Large scale demonstration of a process analytical technology application in bioprocessing: Use of on-line high performance liquid chromatography for making real time pooling decisions for process chromatography (p NA)
Anurag S. Rathore, Lilly Parr, Shinta Dermawan, Ken Lawson, Yuefeng Lu
Published Online: Nov 19 2009 10:59AM
DOI: 10.1002/btpr.320

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Antibody-immobilized column for quick cell separation based on cell rolling (p NA)
Atsushi Mahara, Tetsuji Yamaoka
Published Online: Nov 13 2009 1:28PM
DOI: 10.1002/btpr.354

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Cell Culture and Tissue Engineering

Hybrid promoters directed tBid gene expression to breast cancer cells by transcriptional targeting (p NA)
Samila Farokhimanesh, Fatemeh Rahbarizadeh, Mohammad J. Rasaee, Abbas Kamali, Baratali Mashkani
Published Online: Nov 13 2009 1:28PM
DOI: 10.1002/btpr.353

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Applied Cellular Physiology and Metabolic Engineering

Mutation of bacterium Vibrio gazogenes for selective preparation of colorants (p NA)
Farzaneh Alihosseini, Jozsef Lango, Kou-San Ju, Bruce D. Hammock, Gang Sun
Published Online: Nov 9 2009 10:14AM
DOI: 10.1002/btpr.346

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Review Articles: Applied Cellular Physiology and Metabolic Engineering

Baculovirus P35 protein: An overview of its applications across multiple therapeutic and biotechnological arenas (p NA)
Sudhir Sahdev, Kulvinder Singh Saini, Seyed E. Hasnain
Published Online: Oct 14 2009 11:34AM
DOI: 10.1002/btpr.339

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