Managing erectile dysfunction in hypertension: the effects of a continuous training programme on biomarker of inflammation

doi:10.1111/j.1464-410X.2008.08254.x

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Wiley InterScience

BJU International

Volume 103 Issue 9, Pages 1218 - 1221

Published Online: 8 Dec 2008

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Official journal of the British Association of Urological Surgeons, the Urological Society of Australasia and the Urological Society of India

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Managing erectile dysfunction in hypertension: the effects of a continuous training programme on biomarker of inflammation

Sikiru Lamina, Chuba G. Okoye* and Theophilus T. Dagogo ^†

Physiology Department, Faculty of Medical Sciences, Jimma University, Jimma, Ethiopia, *Medical Rehabilitation Department, Faculty of Health Sciences And Technology, University of Nigeria, Enugu Campus, Enugu, and ^†Department of Medicine, Murtala Muhammed Specialist Hospital, Kano, Nigeria

Correspondence to Sikuru Lamina, Department of Physiology/Physiotherapy, Jimma University, Jimma, Box 378, Jimma, Ethiopia.
e-mail: siklam_86@yahoo.co.uk

KEYWORDS

hypertension • erectile dysfunction • exercise • C-reactive protein

ABSTRACT

To determine the effect of a continuous training programme on C-reactive protein (CRP) levels, and in the management of erectile dysfunction (ED) in older men with hypertension.

PATIENTS AND METHODS

In all, 22 men with hypertension and ED (mean age 61.8 years, sd 7.79) were involved in continuous training (35–59% of heart rate maximum reserve) for 8 weeks for 45–60 min, while 21 age-matched control hypertensives (mean age 64 years, sd 8.53) remained sedentary during this period. The International Index of Erectile Function (IIEF) questionnaire was used to assess the outcome of ED. The Mann–Whitney U-test and Spearman correlation were used to analyse the results of the changes in IIEF and CRP.

RESULTS

There was a significant effect of continuous exercise training on erectile function and CRP levels in hypertensive men with ED (P < 0.05).

CONCLUSIONS

A continuous training programme decreases CRP levels and is an effective means of noninvasive and nonpharmacological management of ED in men with hypertension.

Accepted for publication 12 September 2008

DIGITAL OBJECT IDENTIFIER (DOI)

10.1111/j.1464-410X.2008.08254.x About DOI