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Wiley InterScience

JOURNALS

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Volume 62 Issue 1 (January 2010)


Reviews

Pharmacokinetics of drugs in rats with diabetes mellitus induced by alloxan or streptozocin: comparison with those in patients with type I diabetes mellitus (p 1-23)
Joo H. Lee, Si H. Yang, Jung M. Oh, Myung G. Lee
Published Online: Jan 8 2010 4:16AM
DOI: 10.1211/jpp.62.01.0001

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Research Papers: Pharmaceutics and Drug Delivery

Ketorolac trometamol topical formulations: release behaviour, physical characterization, skin permeation, efficacy and gastric safety (p 25-34)
Doaa Ahmed El-Setouhy, Sahar Mohy Ahmed El-Ashmony
Published Online: Jan 8 2010 4:16AM
DOI: 10.1211/jpp.62.01.0002

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Development of an original method to study drug release from polymeric nanocapsules in the skin (p 35-45)
Valeria Weiss-Angeli, Sandrine Bourgeois, Jocelyne Pelletier, Silvia Stanisçuaski Guterres, Hatem Fessi, Marie-Alexandrine Bolzinger
Published Online: Jan 8 2010 4:16AM
DOI: 10.1211/jpp.62.01.0003

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Research Papers: Biopharmaceutics and Drug Disposition

Glucuronidation of piceatannol by human liver microsomes: major role of UGT1A1, UGT1A8 and UGT1A10 (p 47-54)
Michaela Miksits, Alexandra Maier-Salamon, Thanh Phuong Nha Vo, Michael Sulyok, Rainer Schuhmacher, Thomas Szekeres, Walter Jäger
Published Online: Jan 8 2010 4:16AM
DOI: 10.1211/jpp.62.01.0004

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Assessment of the in-vivo drug release from pellets film-coated with a dispersion of high amylose starch and ethylcellulose for potential colon delivery (p 55-61)
Cristina Freire, Fridrun Podczeck, Dinora Ferreira, Francisco Veiga, João Sousa, Angelina Pena
Published Online: Jan 8 2010 4:16AM
DOI: 10.1211/jpp.62.01.0005

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Effects of polysorbate 80 on the in-vitro precipitation and oral bioavailability of halofantrine from polyethylene glycol 400 formulations in rats (p 63-70)
Henrik Tønsberg, René Holm, Jette Bisgaard, Jette Jacobsen, Anette Müllertz
Published Online: Jan 8 2010 4:16AM
DOI: 10.1211/jpp.62.01.0006

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Intracellular pharmacokinetics of telithromycin, a ketolide antibiotic, in alveolar macrophages (p 71-75)
Kohei Togami, Sumio Chono, Toshinobu Seki, Kazuhiro Morimoto
Published Online: Jan 8 2010 4:16AM
DOI: 10.1211/jpp.62.01.0007

Abstract  |  References | Full Text:   HTML,   PDF (Size: 153K)
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Research Papers: Molecular and Clinical Pharmacology

CPU228, a derivative of dofetilide, relieves cardiac dysfunction by normalizing FKBP12.6, NADPH oxidase and protein kinase C ε in the myocardium (p 77-83)
Khan Hussien Hamed, Chen Hu, De-Zai Dai, Feng Yu, Yin Dai
Published Online: Jan 8 2010 4:16AM
DOI: 10.1211/jpp.62.01.0008

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The role of erythropoietin in the protection of gastric mucosa from indometacin-induced gastric injury and its relationship with oxidant and antioxidant parameters in rats (p 85-90)
Fatih Albayrak, Fehmi Odabasoglu, Zekai Halici, Beyzagul Polat, Hakan Dursun, Abdullah Uyanik, Yasin Bayir, Feride Koc, Halis Suleyman, Yavuz Albayrak
Published Online: Jan 8 2010 4:16AM
DOI: 10.1211/jpp.62.01.0009

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A bioassay for mosquito repellency against Aedes aegypti: method validation and bioactivities of DEET analogues (p 91-97)
Alexander Jahn, Seok Yong Kim, Joon-Ho Choi, Dae-Duk Kim, Young-Joon Ahn, Chul Soon Yong, Jung Sun Kim
Published Online: Jan 8 2010 4:16AM
DOI: 10.1211/jpp.62.01.0010

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Geranylgeranylacetone preconditioning may attenuate heat-induced inflammation and multiorgan dysfunction in rats (p 99-105)
Yong-Qi Zhao, Jun-Tao Gao, Shou-Hong Liu, Yan Wu, Mao-Tsun Lin, Ming Fan
Published Online: Jan 8 2010 4:16AM
DOI: 10.1211/jpp.62.01.0011

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Anti-ischaemic activity of an antioxidant aldose reductase inhibitor on diabetic and non-diabetic rat hearts (p 107-113)
Vincenzo Calderone, Lara Testai, Alma Martelli, Concettina La Motta, Stefania Sartini, Federico Da Settimo, Maria C. Breschi
Published Online: Jan 8 2010 4:16AM
DOI: 10.1211/jpp.62.01.0012

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Research Papers: Drugs from Natural Sources

Aloe vera gel alleviates cardiotoxicity in streptozocin-induced diabetes in rats (p 115-123)
Neeti Jain, Rajagopalan Vijayaraghavan, Satish Chandra Pant, Vinay Lomash, Mohammed Ali
Published Online: Jan 8 2010 4:16AM
DOI: 10.1211/jpp.62.01.0013

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Short Communications

Application of hanging drop technique to optimize human IgG formulations (p 125-131)
Guohua Li, Purna C. Kasha, Sameer Late, Ajay K. Banga
Published Online: Jan 8 2010 4:16AM
DOI: 10.1211/jpp.62.01.0014

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Inhibitory effects of uraemic toxins 3-indoxyl sulfate and p-cresol on losartan metabolism in vitro (p 133-138)
Masayuki Tsujimoto, Keishi Higuchi, Daisuke Shima, Hitoshi Yokota, Taku Furukubo, Satoshi Izumi, Tomoyuki Yamakawa, Masaki Otagiri, Sumio Hirata, Kohji Takara, Kohshi Nishiguchi
Published Online: Jan 8 2010 4:16AM
DOI: 10.1211/jpp.62.01.0015

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Preparation, characterisation and anti-tumour activity of Ganoderma lucidum polysaccharide nanoparticles (p 139-144)
Ni Li, Yu-Lan Hu, Cai-Xia He, Cheng-Jie Hu, Jun Zhou, Gu-Ping Tang, Jian-Qing Gao
Published Online: Jan 8 2010 4:16AM
DOI: 10.1211/jpp.62.01.0016

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JS-K has potent anti-angiogenic activity in vitro and inhibits tumour angiogenesis in a multiple myeloma model in vivo (p 145-151)
Tanyel Kiziltepe, Kenneth C. Anderson, Jeffery L. Kutok, Lee Jia, Kenneth M. Boucher, Joseph E. Saavedra, Larry K. Keefer, Paul J. Shami
Published Online: Jan 8 2010 4:16AM
DOI: 10.1211/jpp.62.01.0017

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